In vivo experiments to determine the efficiency of the elementary status correction

Author:

Kutsova A E,Sergienko I V,Alehina A V,Kosenko I S,Kutsov S V

Abstract

Abstract The article is about the determination of the elementary factors and common elementary human statuses. To assess the effectiveness of the developed therapeutic and prophylactic preparations the analysis of biomedical research products, using weight and growth features, and hematological and biochemical parameters, is given. During the experiment the appearance and behavior of the animals, their appetite and the mass indexes change were controlled. To examine the acute toxicity the investigated product was put into stomachs of white mice and white rats males by the stomach pump. The growing dose could be lethal for most animals within 15 days. The preparation was diluted with the 0,5 cm3 distilled water for the mice and 2 cm 3 for the rats. During the experiment the animals were pithed to estimate the hematology and biochemical indicators of their collected blood. The researches helps to conclude that the developed preparation has obvious anti-anemic effects, does not affect the animal’s health, is a low-toxic chemical substance – 4-th class of toxicity, does not have allergic, embryologic, teratogenic and skin-resorptive features, the accumulation level is weak. Feeding the animals with the preparation did not show any violations of the organs, tissues and the body system. The preparation positively affects the metabolic processes and weight gain of the white rats. The developed anti-anemic preparation is biologically valued. It has high consumer qualities; mass fraction of protein and iron, vitamins and other essential nutrients. The technologies allow producing a wide range of preparation for the children, pregnant and lactating women, patients in rehabilitation period and people affected the harmful factors in accidents at the industrial enterprises, living in risk areas and working in therapeutic and preventive medicine, suffering from iron-deficiency anemia.

Publisher

IOP Publishing

Subject

General Engineering

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