Anti-depression effect and mechanism of Suanzaoren Decoction on mice with depression

Author:

Zhang Huan,Ren Yumei,Lv Meiqi,Xie Mengting,Wang Kai,Yang Mengjie,Lv Chengqi,Li Xiaobing

Abstract

Abstract Objective: To study the therapeutic effect and mechanism of Suanzaoren Decoction on mice with depression. Methods: A model of depression was prepared by chronic unpredictable stimulation and reserpine induction. Behavioral tests, determination of norepinephrine and dopamine were performed. Results: The behavioral indicators of the model group were reduced, and the expression of norepinephrine and dopamine was decreased. Conclusion: Suanzaoren Decoction has an effect on the increase of serum norepinephrine and dopamine content, indicating that the jujube seed Soup has a certain effect on depression.

Publisher

IOP Publishing

Subject

General Engineering

Reference10 articles.

1. The pathogenesis of depression and its treatment progress [J];Xiang;Journal of Clinical Medicine,2017

2. Research and application of anti-depression mechanism of licorice [J];Yang;Chinese Journal of Experimental Traditional Medical Formulae,2016

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