Author:
Sari Yunita,Isworo Atyanti,Upoyo Arif Setyo,Sumeru Annas,Kurniawan Dhadhang Wahyu,Sutrisna Eman
Abstract
Abstract
Banana stem sap (BSS) and virgin coconut oil (VCO) is usually used for wound care treatment. However, to date, no study has been conducted to compare the effectiveness of these two therapies. Therefore, this study aimed to compare the effectiveness of BSS and VCO on diabetic wound healing in rats. Male Wistar rats were randomly divided into 3 groups depending on the formulation used on the wound: BSS, VCO, and control-treated with film dressing. The tissue samples were obtained on days 4, and 14. The wound size, the presence of necrotic tissue, level of inflammation, level of fibroblast, and re-epithelialization were assessed. On day 10, wounds in the BSS group were the smallest compared with other groups. The necrotic tissue and level of inflammation in the BSS group were also less as compared with other groups. The re-epithelialization in BSS group was also the most advance compared with other groups. Our study showed that the ability of BSS in accelerating wound healing is better than VCO and film dressing. We recommend nurses and clinician in Indonesia to use BSS to treat diabetic ulcer.
Reference22 articles.
1. Global estimates of the prevalence of diabetes for 2010 and 2030;Shaw;Diabetes Res. Clin. Pract.,2010
2. Dysregulation of wound healing mechanisms in diabetes and the importance of negative pressure wound therapy (NPWT);Khamaisi;Diabetes. Metab. Res. Rev.,2017
3. Local resource botanicals used in wound care;Haesler;Wound Pr. Res,2016
4. Musa paradisiaca L. and Musa sapientum L. : A Phytochemical and Pharmacological Review Mohammad Zafar Imam and Saleha Akter;Imam;J. Appl. Pharm. Sci.,2011
5. Tryptophan and Indole Compounds in Banana Ovaries;Shanmugavelu;Nature,1962
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献