Antibacterial Effectiveness Of Formulations Nanoemulsion Cratoxylum Glaucum Korth. Extract

Abstract

Abstract Cratoxylum glaucum Korth. is a members of the family Hypericaceae which are spread in Indonesia, one of which is found in the forest of the Bangka Belitung Islands. Cratoxylum glaucum Korth is often used by the people of Bangka Belitung as a flavoring ingredient from ancient times until now it is still consumed and utilized by people around Bangka Belitung. One source of natural antioxidants is the top of the crust. The effort of increasing its activity is very strong, so in this study we try to develop extraction of Cratoxylum glaucum made in the form of nanoemulsion. This study aims to determine the comparison of Cratoxylum glaucum extract in nanoemulsion preparations with extracts as antibacterial. Nanoemulsion is made with the composition of Virgin Coconut Oil (VCO) as an oil phase, tween 80 as surfactant and aquades as a water phase with a ratio of 2.5: 10: 25. The nanoemulsion extract of Cratoxylum glaucum have a size 422.9 nm and PI value 0.493. The antibacterial activity of nanoemulsion formulation has inhibitory growth power in moderate categorized Staphylococcus aureus bacteria, whereas in the extract of Cratoxylum glaucum it has the inhibitory growth of active Staphylococcus aureus bacteria.