Research Progress of Green Immunoassay for Mycotoxins

Abstract

Abstract Mycotoxin pollution not only causes huge economic losses, but also seriously threatens the health of humans and animals. Immunoassay methods are widely used in the rapid detection of mycotoxins, but the method requires the use of toxin standards and artificial antigens.The artificial antigen synthesis is not only difficult to prepare, but also requires toxin standards as raw materials. Toxin standards are expensive and harmful to the health of producers and operators, which restricts the application and popularization of immunoanalytic methods in mycotoxin detection. If the toxic antigens and standards involving in the immune reaction is substituted with the non-toxic antigen, a green immunology test method can be established to overcome the above deficiencies. Establishing a green, fast, simple and highly sensitive immunoassay method to detect these toxins has become a hot topic in recent years. This paper reviews the application and prospect of green immunoanalysis methods based on anti-unique antibody and phage display techniques inmycotoxins.