Determination of chronic toxicity of glyphosate by biotesting in laboratory mice

Abstract

Abstract Glyphosate is the most promising herbicide currently used throughout the world. Glyphosate-containing preparations are also used as a desiccant in the pre-harvest period. Repeated processing of agricultural plants during the growth period and immediately before harvesting contributes to the accumulation of the herbicide in residual amounts in crops. The article presents the results of chronic intoxication of laboratory mice. It has been shown that glyphosate in residual amounts of 7, 14, 28 mg/kg is capable of causing quantitative and qualitative changes in formed blood cells, inhibits the functions of the reproductive system of experimental animals, and promotes changes in the structure of parenchymal organs. Experimental data indicate chronic toxicity of glyphosate at low concentrations.