Anti-Obesity Effect of Yoghurt Synbiotic in High Fat Diet Induced Wistar Rats

Abstract

Abstract The prevalence of obesity which tends to increase is also known to be one of the triggers for various degenerative diseases. The main reason for obesity is unbalanced lifestyle. One solution that can be applied in overcoming the problem of degenerative diseases is by consuming functional food such as probiotics. Probiotics are mostly familiar in fermented products, especially milk-based products as well as yoghurt. This study uses yoghurt added with sweet potatoes containing Lactococcus lactis subsp. cremoris and Streptococcus salivarius subsp thermophilus as a starter culture. This study aims to determine the effect of giving synbiotic yoghurt towards body weight’s decrease in wistar rats feed under a high-fat diet. In this study, 24 wistar rats were grouped into 4 treatment groups particularly P1 (control); P2 (by giving yoghurt with a dose of 1 ml per day); P3 (1.5 ml per day); and P4 (2.5 ml per day). The treatment is carried out for 3 weeks and weighing is done every week. The results showed that the treatment group had the ability to reduce body weight significantly (p<0.05) compared to the control group.