Application and prospect of semiconductor biosensors in detection of viral zoonoses

Abstract

Abstract The rapid spread of viral zoonoses can cause severe consequences, including huge economic loss, public health problems or even global crisis of society. Clinical detection technology plays a very important role in the prevention and control of such zoonoses. The rapid and accurate detection of the pathogens of the diseases can directly lead to the early report and early successful control of the diseases. With the advantages of being easy to use, fast, portable, multiplexing and cost-effective, semiconductor biosensors are kinds of detection devices that play an important role in preventing epidemics, and thus have become one of the research hotspots. Here, we summarized the advances of semiconductor biosensors in viral zoonoses detection. By discussing the major principles and applications of each method for different pathogens, this review proposed the directions of designing semiconductor biosensors for clinical application and put forward perspectives in diagnostic of viral zoonoses.