Abstract
Abstract
Chemical pollutants such as heavy metals and antibiotics in the environment pose a huge threat to humans and animals. Our studies have demonstrated that the fluorescence of phycocyanin showed quenching responses towards both mercury (Hg2+) and ciprofloxacin (CIP), which acted in accordance with the ‘OR’ molecular logic gate. In order to discriminate Hg2+ and CIP in application scenarios, cysteine (Cys) was utilized to design another ‘INHIBIT’ logic gate, in which Hg2+ and Cys were the two inputs. Thus, an intelligent biosensor with dual-target identification capacity was successfully developed by using a fluorescent natural protein in an ingenious logic gate system.
Funder
the National Key Research and Development Program of China
the Open Project of Engineering Research Center of Dairy Quality and Safety Control Technology
Subject
Spectroscopy,General Materials Science,Instrumentation,Atomic and Molecular Physics, and Optics
Cited by
1 articles.
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