Biodegradable behavior and antibacterial activities of a novel Zn-0.5%Li-(Ag) alloys

Author:

Lu YujiaoORCID,Xu XuemeiORCID,Liu Hui,Liu Ying,Fang Hongjie,Dai YilongORCID,Yan Yang,Yu Kun

Abstract

Abstract In this work, a novel Zn-0.5%Li-(Ag) alloys were successfully prepared by molten casting technology, and the microstructure, mechanical properties and the biodegradation behavior of Zn-based alloys in a Dulbecco’s modified Eagle’s medium (fetal bovine serum) were assessed. Additionally, their antibacterial properties were investigated by assaying the cell viability of bone marrow mesenchymal stem cells and by disc diffusion antibiotic sensitivity testing. The alloys had a reduced corrosion rate due a grain refinement effect (through more readily passivation) provided by nano-LiZn4 precipitates and Zn(OH)2/ZnO and ZnCO3 spontaneous precipitation on the surface. The Zn-0.5%Li-0.2%Ag alloy has no cytotoxicity, and which achieved highest mechanical properties ( tensile strengths of 278.3MPa and percentage elongation (ε) of 96.2%) and excellent antibacterial properties.

Funder

Scientific research project of Hunan Education Department

the science and technology innovation Program of Hunan Province

the foundation of National Key laboratory of Shock Wave and Detonation Physics

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province of China

National Key laboratory of Shock Wave and Detonation Physics

Publisher

IOP Publishing

Subject

Metals and Alloys,Polymers and Plastics,Surfaces, Coatings and Films,Biomaterials,Electronic, Optical and Magnetic Materials

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