Author:
Yan Yongnian,Wu Rendong,Zhang Renji,Xiong Zhuo,Lin Feng
Abstract
This paper introduces a new subject called bio‐manufacturing. Bio‐manufacturing combines life science with manufacturing science, and uses manufacturing method to form materials with bio‐activity and bio‐degradability into scaffolds. In this paper, we discuss the hierarchy of bio‐manufacturing: the lower grade uses undegradable bio‐material to form permanent organ replacement such as auricular cartilage and the higher grade uses biodegradable bio‐materials to repair organ damage or organ replacement which degrades after embedded in the human body. They all adopt jetting/extrusion deposition process (fused deposition modelling or 3D printer), the distinct different point being the temperature of the forming chamber. The samples of bones and auricular cartilage produced by those processes had been practiced on dogs and rabbits, repaired their damage.
Subject
Industrial and Manufacturing Engineering,Mechanical Engineering
Reference8 articles.
1. Hutmacher, D.W. (2000), “Scaffolds in tissue engineering bone and cartilage”, Biomaterials, Vol. 21, pp. 2529–43.
2. Langer, R. and Vacanti, J. (1993), “Tissue engineering”, Science, Vol. 260, pp. 920–6.
3. Nam, Y.S. and Park, T.G. (1999), “Porous biodegradable polymeric scaffolds prepared by thermally induced phase separation”, J. Biomed. Mater. Res., Vol. 4 No. 1, pp. 8–17.
4. Wang, Li and Yongnian, Yan et al. (2001), “Analysis and realization of bone tissue engineering cell scaffold”, Material Guide, Vol. 15 No. 11 pp. 49–51.
5. Xing xin et al. (2000), Porous high density polyethylene implants (MedPor) for repair of skull defects and sunken deformities: a report of 6 cases, Applied Beauty and Plastic Surgery, Vol. 11 No. 6, pp. 281‐4.
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