Precision extruding deposition and characterization of cellular poly‐ε‐caprolactone tissue scaffolds

Author:

Wang F.,Shor L.,Darling A.,Khalil S.,Sun W.,Güçeri S.,Lau A.

Abstract

Successes in scaffold guided tissue engineering require scaffolds to have specific macroscopic geometries and internal architectures to provide the needed biological and biophysical functions. Freeform fabrication provides an effective process tool to manufacture many advanced scaffolds with designed properties. This paper reports our recent study on using a novel precision extruding deposition (PED) process technique to directly fabricate cellular poly‐ε_rm;‐caprolactone (PCL) scaffolds. Scaffolds with a controlled pore size of 250 μm and designed structural orientations were fabricated.

Publisher

Emerald

Subject

Industrial and Manufacturing Engineering,Mechanical Engineering

Reference17 articles.

1. Bellini, A. (2002) “Fused deposition of ceramics: a comprehensive experimental, analytical and computational study of material behavior, fabrication process and equipment design”, PhD dissertation, Department of Mechanical Engineering and Mechanics, Drexel University.

2. Hollister, S.J., Maddox, R.D. and Taboas, J.M. (2002), “Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints”, Biomaterials, Vol. 23, pp. 4095‐103.

3. Hutmacher, D.W. (2000), “Scaffolds in tissue engineering bone and cartilage”, Biomaterials, Vol. 21, pp. 2529‐43.

4. Koch, K.U., Biesinger, B., Arnholz, C. and Jansson, V. (1998), “Creating of bio‐compatible, high stress resistant and resorbable implants using multiphase jet solidification technology”, Rapid News Publication, pp. 209‐14.

5. Lin, A.S.P., Barrows, T.H., Cartmell, S.H. and Guldberg, R.E. (2003), “Micro‐architectural and mechanical characterization of oriented porous polymer scaffolds”, Biomaterials, Vol. 24, pp. 481‐9.

Cited by 193 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3