Author:
Jin Yongjun,Cui Haihang,Chen Li,Liu Zhe,Sun Kai
Abstract
Purpose
The purpose of this paper is to study the mechanism of efficient sputum excretion from the distal lung by using a tessellationally distal lung model with alveolar pores.
Design/methodology/approach
First, a two-dimensional tessellational composite structure of the bronchus, alveoli and alveolar pores (Kohn pore) is constructed with the tessellational splitting and fusion of regular hexagonal elements. Then, the level set method is used to study the effects of alveolar pores and their sizes, expiratory cycles and respiratory intensity.
Findings
The existence of alveolar pores is the prerequisite for sputum excretion, and there is an optimal size of alveolar pores for sputum excretion. Strong asymmetric respiration can break the reversibility of the flow at a low Reynolds number and causes significant net displacement of sputum. The expiratory cycle is negatively correlated with the net displacement of sputum. The respiratory intensity is positively correlated with the net displacement of sputum.
Originality/value
This research is helpful for understanding the complex sputum excretion process in diseases, such as pneumonia, and developing corresponding adjuvant therapy.
Subject
Applied Mathematics,Computer Science Applications,Mechanical Engineering,Mechanics of Materials
Cited by
2 articles.
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