Author:
Zhang Xiaoyan,Wang Runtian,Zhao Yingyu,Zhang Jun,Zhang Boyuan,Chen Zhengcan,Liu Pu,Chen Zhenbin,Liu Chunli,Li Xiaoming
Abstract
Purpose
This paper aims to evaluate the separation and purification characteristics of flavonoids from polygonum cuspidatum (PC) extracts by using macroporous adsorption resins (MAR) mixed bed to improve the utilization rate of flavonoids.
Design/methodology/approach
Taking the separation performance of flavonoids as an evaluation index, the best MAR were screened from 31 sorts of MAR and combined the best MAR to form a MAR mixed bed for adsorption and separation of flavonoids.
Findings
By studying the separation conditions that affect flavonoids, the results showed that resin LZ-72 has best separation and purification effect on flavonoids under the optimal adsorption and desorption conditions, the purity of the obtained flavonoid compound reaches 82.50%, 2.66 times of the initial extract, and the recovery rate reaches 89.70%. Theoretical research results have shown that the adsorption of flavonoids by MAR conforms to the pseudo-second-order kinetics and Freundlich models.
Practical implications
Because the flavonoids in PC have great medicinal value, the purpose of this work is to develop a method of separating and purifying flavonoids from PC, which will provide a certain foundation for the development of medicine.
Originality/value
This contribution provided a novel way to separate flavonoids from PC. Under the optimal conditions, the content of flavonoids in the product was increased 2.66-fold from 31.01% to 82.50%, and the recovery yield was 89.70%.
Subject
Materials Chemistry,Surfaces, Coatings and Films
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