Author:
Elsharkawy Eman E.,El-Nisr Neveen A.,Wahba Nahed M.,Elsherif Walaa M.
Abstract
Purpose
The purpose of this paper is to investigate the restoration effect of camel's milk against methoxychlor induced liver toxicity.
Design/methodology/approach
The present study was carried out to investigate the restoration effect of camel's milk against methoxychlor induced liver toxicity.
Findings
Methoxychlor (MXC) caused a significant increase in serum transaminases (aspartate transaminase and alanine transaminase) and alkaline phosphatase, while MXC induced a significant reduction in total protein and albumin levels. MXC significantly inhibited lipid peroxidation and markedly enhanced glutathione in liver homogenate. Pathological damages as degeneration and coagulative necrosis of hepatocytes were established in liver. Newly formed bile ducteules denotes neoplastic changes in the portal tract with abnormal mitotic pattern were associated with the long-term exposure.
Originality/value
The present study concluded that camel milk treatment may play a protective role against methoxychlor-induced liver damage in rats.
Subject
Nutrition and Dietetics,Food Science
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