The association of lifeline diet score (LLDS) with risk of irritable bowel syndrome: case-control study in adult men

Abstract

Purpose Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder that significantly impacts the quality of life of affected individuals. Diet has been identified as a potential modifiable risk factor for IBS, yet its association with IBS risk in the Kurdish adult male population remains understudied. This case-control study aimed to investigate the association between the lifeline diet score (LLDS), a validated tool assessing overall diet quality and the risk of IBS in Kurdish adult men. Design/methodology/approach A total of 200 Kurdish adult men were recruited, comprising 100 IBS patients (cases) and 100 healthy controls without IBS. Medical records and interview questionnaires were used to confirm IBS diagnoses, while detailed dietary questionnaires were administered to assess participants’ dietary habits and calculate their respective LLDS scores. Logistic regression analysis was used to examine the association between LLDS and IBS risk, adjusting for potential confounding factors. Findings Participants with higher LLDS scores exhibited a significantly reduced risk of IBS compared to those with lower LLDS scores (OR= 0.38, 95% confidence intervals = 0.18–0.77; p <0.001). The association remained statistically significant even after controlling for potential confounders such as socioeconomic status, age, eating rate, protein, fat, physical activity and body mass index. Originality/value This case-control study demonstrates a significant inverse association between the LLDS and the risk of IBS in Kurdish adult men. Higher LLDS scores, indicative of a healthier and more balanced diet, were associated with a decreased risk of IBS. These findings highlight the potential role of dietary patterns in IBS prevention and management within the Kurdish adult male population.