Biosymbiotic platform for chronic long-range monitoring of biosignals in limited resource settings

Author:

Stuart Tucker1ORCID,Farley Max1ORCID,Amato Julia1ORCID,Thien Ryan1ORCID,Hanna Jessica1,Bhatia Aman1ORCID,Clausen David Marshall1ORCID,Gutruf Philipp1234ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721

2. Department of Electrical and Computer Engineering, University of Arizona, Tucson, AZ 85721

3. Bio5 Institute, University of Arizona, Tucson, AZ 85721

4. Neuroscience Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ 85721

Abstract

Remote patient monitoring is a critical component of digital medicine, and the COVID-19 pandemic has further highlighted its importance. Wearable sensors aimed at noninvasive extraction and transmission of high-fidelity physiological data provide an avenue toward at-home diagnostics and therapeutics; however, the infrastructure requirements for such devices limit their use to areas with well-established connectivity. This accentuates the socioeconomic and geopolitical gap in digital health technology and points toward a need to provide access in areas that have limited resources. Low-power wide area network (LPWAN) protocols, such as LoRa, may provide an avenue toward connectivity in these settings; however, there has been limited work on realizing wearable devices with this functionality because of power and electromagnetic constraints. In this work, we introduce wearables with electromagnetic, electronic, and mechanical features provided by a biosymbiotic platform to realize high-fidelity biosignals transmission of 15 miles without the need for satellite infrastructure. The platform implements wireless power transfer for interaction-free recharging, enabling long-term and uninterrupted use over weeks without the need for the user to interact with the devices. This work presents demonstration of a continuously wearable device with this long-range capability that has the potential to serve resource-constrained and remote areas, providing equitable access to digital health.

Funder

Flinn Foundation

National Science Foundation

University of Arizona

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

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