Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference23 articles.
1. Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors
2. Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
3. Edible vaccines: not quite ready for prime time
4. Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
5. Life at the edge: the nuclear envelope and human disease
Cited by 249 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. TIPE2 gene transfer ameliorates aging-associated osteoarthritis in a progeria mouse model by reducing inflammation and cellular senescence;Molecular Therapy;2024-09
2. Progerin forms an abnormal meshwork and has a dominant-negative effect on the nuclear lamina;Proceedings of the National Academy of Sciences;2024-06-25
3. Differential Expression of LMNA/C and Insulin Receptor Transcript Variants in Peripheral Blood Mononuclear Cells of Leukemia Patients;Journal of Clinical Medicine;2024-04-27
4. Deciphering the role of neddylation in tumor microenvironment modulation: common outcome of multiple signaling pathways;Biomarker Research;2024-01-08
5. The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B;Nucleus;2023-12-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3