Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
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1. An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins.
2. Preventing the Spontaneous Modification of an HLA-A2-Restricted Peptide at an N-Terminal Glutamine or an Internal Cysteine Residue Enhances Peptide Antigenicity
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