Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition-Reference-Cited by-同舟云学术

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Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition

Published:2009-12-28 Issue:4 Volume:107 Page:1630-1635
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Jiang Y.,Mullaney K. A.,Peterhoff C. M.,Che S.,Schmidt S. D.,Boyer-Boiteau A.,Ginsberg S. D.,Cataldo A. M.,Mathews P. M.,Nixon R. A.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference34 articles.

1. Amyloid β-peptide is produced by cultured cells during normal metabolism

2. Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

3. Role of the β‐amyloid protein in Alzheimer's disease

4. Polymorphisms in the Promoter of the Human APP Gene

5. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

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5. Hippocampal CA1 Pyramidal Neurons Display Sublayer and Circuitry Dependent Degenerative Expression Profiles in Aged Female Down Syndrome Mice;Journal of Alzheimer's Disease;2024-08-20

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