Assembly of the neutrophil respiratory burst oxidase: A direct interaction between p67PHOX and cytochrome b558
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference23 articles.
1. NADPH Oxidase: An Update
2. Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation.
3. Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes
4. The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase.
5. A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.
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