Ligation of CD8 leads to apoptosis of thymocytes that have not undergone positive selection
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference45 articles.
1. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
2. Evidence for a differential avidity model of T cell selection in the thymus
3. T-cell-receptor affinity and thymocyte positive selection
4. Antigen-induced apoptosis in developing t cells: a mechanism for negative selection of the t cell receptor repertoire*
5. Interleukin-2 receptor common γ-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression
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3. In vivo depletion of leukocytes and platelets following injection of T cell-specific antibodies into mice;Journal of Immunological Methods;2013-07
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