Repair of thalassemic human -globin mRNA in mammalian cells by antisense oligonucleotides
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference22 articles.
1. FREQUENCIES OF COMMON β-THALASSAEMIA ALLELES AMONG DIFFERENT POPULATIONS: VARIABILITY IN CLINICAL SEVERITY
2. beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.
3. RNA transcripts of the β-thalassaemia allele IVS-2–654 C → T: a small amount of normally processed β-globin mRNA is still produced from the mutant gene
4. β+ Thalassemia: Aberrant splicing results from a single point mutation in an intron
5. Abnormally spliced messenger RNA in erythroid cells from patients with β+ thalassemia and monkey cells expressing a cloned β+-thalassemic gene
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