The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference27 articles.
1. Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts.
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3. Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport
4. Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis
5. Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene
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