Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference34 articles.
1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
2. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
3. Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo
4. Choosing and using Drosophila models to characterize modifiers of Huntington's disease
5. A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila
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