Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference24 articles.
1. Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution ofβ-Hydroxyketones with Aldolase Antibodies
2. Sets of Aldolase Antibodies with Antipodal Reactivities. Formal Synthesis of Epothilone E by Large-Scale Antibody-Catalyzed Resolution of Thiazole Aldol
3. Efficient Aldolase Catalytic Antibodies That Use the Enamine Mechanism of Natural Enzymes
4. Broadening the Aldolase Catalytic Antibody Repertoire by Combining Reactive Immunization and Transition State Theory: New Enantio- and Diastereoselectivities
5. Multiple event activation of a generic prodrug trigger by antibody catalysis
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