HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference29 articles.
1. HIV-Protease Inhibitors
2. Cardiovascular Risks of Antiretroviral Therapies
3. Cardiovascular Risk and Body-Fat Abnormalities in HIV-Infected Adults
4. Evaluation and management of dyslipidemia in patients with HIV infection
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1. Navigating Lipodystrophy: Insights from Laminopathies and Beyond;International Journal of Molecular Sciences;2024-07-23
2. The Compromised Fanconi Anemia Pathway in Prelamin A‐Expressing Cells Contributes to Replication Stress‐Induced Genomic Instability;Advanced Science;2024-06-18
3. Reduced ZMPSTE24 expression leads to prelamin accumulation and development of steatosis in MASLD patients;2024-05-20
4. A lipid index for risk of hyperlipidemia caused by anti-retroviral drugs;Antiviral Research;2024-03
5. The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B;Nucleus;2023-12-05
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