Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference31 articles.
1. The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate
2. Human cancer, PTEN and the PI-3 kinase pathway
3. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway
4. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
5. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
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