3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase

Author:

Torreira Eva,Tortajada Agustín,Montes Tamara,de Córdoba Santiago Rodríguez,Llorca Oscar

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference31 articles.

1. Volanakis JE (1998) The Human Complement System in Health and Disease (Marcel Dekker, Inc. New York), 10th Ed. pp 9–32.

2. The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase;Pangburn;Biochem J,1986

3. Interactions of human complement component C3 with factor B and with complement receptors type 1 (CR1, CD35) and type 3 (CR3, CD11b/CD18) involve an acidic sequence at the N-terminus of C3 α-chain;Taniguchi-Sidle;J Immunol,1994

4. Engineering of human complement component C3 for catalytic inhibition of complement;Kölln;Immunol Lett,2005

5. Complement inactivation by recombinant human C3 derivatives;Kölln;J Immunol,2004

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