Molecular actions of smoking cessation drugs at 4 2 nicotinic receptors defined in crystal structures of a homologous binding protein-Reference-Cited by-同舟云学术

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Molecular actions of smoking cessation drugs at 4 2 nicotinic receptors defined in crystal structures of a homologous binding protein

Published:2012-05-22 Issue:23 Volume:109 Page:9173-9178
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Billen B.,Spurny R.,Brams M.,van Elk R.,Valera-Kummer S.,Yakel J. L.,Voets T.,Bertrand D.,Smit A. B.,Ulens C.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference39 articles.

1. Nicotine activates and desensitizes midbrain dopamine neurons

2. Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

3. Nicotine Activation of α4* Receptors: Sufficient for Reward, Tolerance, and Sensitization

4. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

5. Novel Pharmacological Approaches for Treating Tobacco Dependence and Withdrawal

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1. Reduction of nicotine and ethanol intake in alcohol-preferring (UChB) female rats by the α4β2 nicotinic acetylcholine receptor partial agonists 5-bromocytisine and cytisine;Drug and Alcohol Dependence;2023-09

2. Pharmacophore Mapping Combined with dbCICA Reveal New Structural Features for the Development of Novel Ligands Targeting α4β2 and α7 Nicotinic Acetylcholine Receptors;Molecules;2022-11-25

3. Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor;Journal of the American Chemical Society;2022-08-25

4. Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (−)-hosieine-A;Acta Crystallographica Section F Structural Biology Communications;2022-08-09

5. Interactions between 2′-fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine-binding protein inform on potent antagonist activity against nicotinic receptors;Acta Crystallographica Section D Structural Biology;2022-02-21

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