Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference55 articles.
1. Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2. Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)
3. Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.
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1. Molecular Mechanism of Activation-Induced Cytidine Deaminase;Molecular Biology of B Cells;2024
2. Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase;Proceedings of the National Academy of Sciences;2023-04-24
3. Necessity of HuR/ELAVL1 for the activation-induced cytidine deaminase-dependent decrease in topoisomerase 1 in antibody diversification;International Immunology;2023-04-22
4. The IgH Eµ-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation;Frontiers in Immunology;2023-02-14
5. Topoisomerases in Immune Cell Development and Function;The Journal of Immunology;2023-01-15
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