Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop-Reference-Cited by-同舟云学术

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Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

Published:2012-03-26 Issue:15 Volume:109 Page:5687-5692
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Eicher T.,Cha H.-j.,Seeger M. A.,Brandstatter L.,El-Delik J.,Bohnert J. A.,Kern W. V.,Verrey F.,Grutter M. G.,Diederichs K.,Pos K. M.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference42 articles.

1. Mechanisms of RND multidrug efflux pumps

2. Substrate Specificity of the RND-Type Multidrug Efflux Pumps AcrB and AcrD of Escherichia coli Is Determined Predominately by Two Large Periplasmic Loops

3. Insertion of inverted Ter sites into the terminus region of the Escherichia coli chromosome delays completion of DNA replication and disrupts the cell cycle

4. Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli

5. The assembled structure of a complete tripartite bacterial multidrug efflux pump

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4. Screening and Evaluation of Potential Efflux Pump Inhibitors with a Seaweed Compound Diphenylmethane-Scaffold against Drug-Resistant Escherichia coli;Antibiotics;2024-07-05

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