Timing social distancing to avert unmanageable COVID-19 hospital surges

Author:

Duque DanielORCID,Morton David P.ORCID,Singh BismarkORCID,Du Zhanwei,Pasco RemyORCID,Meyers Lauren AncelORCID

Abstract

Following the April 16, 2020 release of theOpening Up America Againguidelines for relaxing coronavirus disease 2019 (COVID-19) social distancing policies, local leaders are concerned about future pandemic waves and lack robust strategies for tracking and suppressing transmission. Here, we present a strategy for triggering short-term shelter-in-place orders when hospital admissions surpass a threshold. We use stochastic optimization to derive triggers that ensure hospital surges will not exceed local capacity and lockdowns are as short as possible. For example, Austin, Texas—the fastest-growing large city in the United States—has adopted a COVID-19 response strategy based on this method. Assuming that the relaxation of social distancing increases the risk of infection sixfold, the optimal strategy will trigger a total of 135 d (90% prediction interval: 126 d to 141 d) of sheltering, allow schools to open in the fall, and result in an expected 2,929 deaths (90% prediction interval: 2,837 to 3,026) by September 2021, which is 29% of the annual mortality rate. In the months ahead, policy makers are likely to face difficult choices, and the extent of public restraint and cocooning of vulnerable populations may save or cost thousands of lives.

Funder

HHS | National Institutes of Health

DHS | Science and Technology Directorate

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference22 articles.

1. An interactive web-based dashboard to track COVID-19 in real time

2. The White House andCenters for Disease Control andPrevention , Guidelines Opening Up America Again (US White House Office, 2020).

3. The effect of public health measures on the 1918 influenza pandemic in U.S. cities

4. The impacts of simultaneous disease intervention decisions on epidemic outcomes;Andrews;J. Theor. Biol.,2016

5. D. Z. Roth , B. Henry , “Social distancing as a pandemic influenza prevention measure” (National Collaborating Centre for Infectious Diseases, 2011). https://nccid.ca/publications/social-distancing-as-a-pandemic-influenza-prevention-measure. Accessed 5 May 2020.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3