Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference34 articles.
1. Keeping Uracil Out of DNA: Physiological Role, Structure and Catalytic Mechanism of dUTPases
2. Homotrimeric dUTPases; Structural Solutions for Specific Recognition and Hydrolysis of dUTP
3. Flexible glycine rich motif ofEscherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme
4. Glycine Rich P-loop Motif in Deoxyuridine Pyrophosphatase
5. The complete triphosphate moiety of non-hydrolyzable substrate analogues is required for a conformational shift of the flexible C-terminus inE. colidUTP pyrophosphatase
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3. Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies;Viruses;2021-10-28
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