Analysis of human cytochrome P450 3A4 cooperativity: Construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics-Reference-Cited by-同舟云学术

Analysis of human cytochrome P450 3A4 cooperativity: Construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

Published:1998-06-09 Issue:12 Volume:95 Page:6636-6641
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Harlow G. R.,Halpert J. R.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference28 articles.

1. Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene

2. Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues.

3. CYP3A gene expression in human gut epithelium

4. Identification of Three Key Residues in Substrate Recognition Site 5 of Human Cytochrome P450 3A4 by Cassette and Site-Directed Mutagenesis

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