Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea-Reference-Cited by-同舟云学术

Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea

Published:1998-02-17 Issue:4 Volume:95 Page:1635-1640
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Engelbergs J.,Thomale J.,Galhoff A.,Rajewsky M. F.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference52 articles.

1. Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.

2. The Prevention of Thymic Lymphomas in Transgenic Mice by Human O 6 -Alkylguanine-DNA Alkyltransferase

3. O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.

4. DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

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