ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference35 articles.
1. Oncogenic Transcription Factors in the Human Acute Leukemias
2. t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.
3. Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
4. The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
5. The runt domain identifies a new family of heterometric transcriptional regulators
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