The A -globin 3' element provides no unique function(s) for human -globin locus gene regulation
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference26 articles.
1. Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
2. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids
3. Position-independent, high-level expression of the human β-globin gene in transgenic mice
4. An enhancer element lies 3′ to the human A gamma globin gene.
5. Human γ-globin genes silenced independently of other genes in the β-globin locus
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1. Persistent Fetal γ-Globin Expression in Adult Transgenic Mice following Deletion of Two Silencer Elements Located 3′ to the Human Aγ-Globin Gene;Molecular Medicine;2009-08-10
2. Silencing of A γ-Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the −566 GATA Site;Molecular and Cellular Biology;2008-05-15
3. Locus control region elements HS2 and HS3 in combination with chromatin boundaries confer high-level expression of a human β-globin transgene in a centromeric region;Genes to Cells;2004-11
4. Negative regulation of γ-globin gene expression by cyclic AMP-dependent pathway in erythroid cells;Experimental Hematology;2004-03
5. An embryonic-specific repressor element located 3′ to the Aγ-globin gene influences transcription of the human β-globin locus in transgenic mice;Experimental Hematology;2004-02
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