Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the absence of germinal centers-Reference-Cited by-同舟云学术

Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the absence of germinal centers

Published:1998-11-24 Issue:24 Volume:95 Page:14343-14348
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Diaz M.,Greenberg A. S.,Flajnik M. F.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference40 articles.

1. Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity.

2. A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks

3. Evolution of somatic hypermutation and gene conversion in adaptive immunity

4. Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

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