Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma-Reference-Cited by-同舟云学术

Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma

Published:1998-03-03 Issue:5 Volume:95 Page:2475-2480
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Lode H. N.,Dreier T.,Xiang R.,Varki N. M.,Kang A. S.,Reisfeld R. A.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

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1. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

2. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

3. ScienceScope

4. Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors.

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