Interferometric mapping of material properties using thermal perturbation

Author:

Goetz GeorgesORCID,Ling TongORCID,Gupta Tushar,Kang Seungbum,Wang Jenny,Gregory Patrick D.,Park B. Hyle,Palanker Daniel

Abstract

Optical phase changes induced by transient perturbations provide a sensitive measure of material properties. We demonstrate the high sensitivity and speed of such methods, using two interferometric techniques: quantitative phase imaging (QPI) in transmission and phase-resolved optical coherence tomography (OCT) in reflection. Shot-noise–limited QPI can resolve energy deposition of about 3.4 mJ/cm2 in a single pulse, which corresponds to 0.8 °C temperature rise in a single cell. OCT can detect deposition of 24 mJ/cm2 energy between two scattering interfaces producing signals with about 30-dB signal-to-noise ratio (SNR), and 4.7 mJ/cm2 when SNR is 45 dB. Both techniques can image thermal changes within the thermal confinement time, which enables accurate single-shot mapping of absorption coefficients even in highly scattering samples, as well as electrical conductivity and many other material properties in biological samples at cellular scale. Integration of the phase changes along the beam path helps increase sensitivity, and the signal relaxation time reveals the size of hidden objects. These methods may enable multiple applications, ranging from temperature-controlled retinal laser therapy or gene expression to mapping electric current density and characterization of semiconductor devices with rapid pump–probe measurements.

Funder

HHS | National Institutes of Health

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference53 articles.

1. Thermal nondestructive testing of carbon epoxy composites: Detailed analysis and data processing;Vavilov;NDT E Int,1993

2. Maldague X (2001) Theory and Practice of Infrared Technology for Nondestructive Testing, Wiley Series in Optical and Microwave Engineering (Wiley, Hoboken, NJ).

3. Review of pulsed thermal NDT: Physical principles, theory and data processing;Vavilov;NDT E Int,2015

4. 3D thermal tomography with experimental measurement data;Toivanen;Int J Heat Mass Transf,2014

5. Comparison and analysis of acoustography with other NDE techniques for foreign object inclusion detection in graphite epoxy composites;Poudel;Compos B Eng,2015

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3