Predominant VH genes expressed in innate antibodies are associated with distinctive antigen-binding sites
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference30 articles.
1. A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection
2. Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies.
3. Normal mouse peritoneum contains a large population of Ly-1+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes.
4. Phosphatidyl choline is recognized by a series of Ly-1+ murine B cell lymphomas specific for erythrocyte membranes.
5. All VH11 genes expressed in peritoneal lymphocytes encode anti-bromelain-treated mouse red blood cell autoantibodies but other VH gene families contribute to this specificity
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