Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication-Reference-Cited by-同舟云学术

Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication

Published:2000-01-04 Issue:1 Volume:97 Page:418-423
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Harth G.,Zamecnik P. C.,Tang J.-Y.,Tabatadze D.,Horwitz M. A.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference25 articles.

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2. Glutamine synthetase of Mycobacterium tuberculosis: extracellular release and characterization of its enzymatic activity.

3. Expression and Efficient Export of Enzymatically ActiveMycobacterium tuberculosis Glutamine Synthetase in Mycobacterium smegmatis and Evidence That the Information for Export is Contained within the Protein

4. An Inhibitor of Exported Mycobacterium tuberculosis Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets

5. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

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