High metastatic potential in mice inheriting a targeted p53 missense mutation
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference25 articles.
1. Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene
2. Overproduction of p53 antigen makes established cells highly tumorigenic
3. The p53 proto-oncogene can act as a suppressor of transformation
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1. In Silico Screening, Molecular Dynamics Simulation and Binding Free Energy Identify Single‐Point Mutations That Destabilize p53 and Reduce Binding to DNA;Proteins: Structure, Function, and Bioinformatics;2024-09-12
2. tp53R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes;2024-08-03
3. Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability;Molecular Systems Biology;2024-04-05
4. Multidimensional quantitative phenotypic and molecular analysis reveals neomorphic behaviors of p53 missense mutants;npj Breast Cancer;2023-09-29
5. Protein-level mutant p53 reporters identify druggable rare precancerous clones in noncancerous tissues;Nature Cancer;2023-08-03
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