Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription-Reference-Cited by-同舟云学术

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Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription

Published:2009-02-23 Issue:10 Volume:106 Page:3907-3912
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Chen Y.,Zhou K.,Wang R.,Liu Y.,Kwak Y.-D.,Ma T.,Thompson R. C.,Zhao Y.,Smith L.,Gasparini L.,Luo Z.,Xu H.,Liao F.-F.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference54 articles.

1. The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

2. The Alzheimer's disease Beta-secretase enzyme, BACE1

3. Pathological and physiological functions of presenilins

4. Diabetes mellitus and the risk of dementia: The Rotterdam Study

5. Diabetes mellitus in midlife and the risk of dementia three decades later

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