Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins
Author:
Affiliation:
1. Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130
2. Center for Science & Engineering of Living Systems, Washington University in St. Louis, St. Louis, MO 63130
Abstract
Funder
HHS | NIH | National Institute of Neurological Disorders and Stroke
DOD | USAF | AMC | Air Force Office of Scientific Research
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Link
https://pnas.org/doi/pdf/10.1073/pnas.2200559119
Reference113 articles.
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3. Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System
4. Fuzzy Complexes: A More Stochastic View of Protein Function
5. Binding without folding – the biomolecular function of disordered polyelectrolyte complexes
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