Will microfluidics enable functionally integrated biohybrid robots?-Reference-Cited by-同舟云学术

Will microfluidics enable functionally integrated biohybrid robots?

Published:2022-08-24 Issue:35 Volume:119 Page:
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proc. Natl. Acad. Sci. U.S.A.

Author:

Filippi Miriam¹^ORCID,Yasa Oncay¹,Kamm Roger Dale²³^ORCID,Raman Ritu³,Katzschmann Robert K.¹^ORCID

Affiliation:

1. Soft Robotics Laboratory, Department of Mechanical Engineering, Eidgenossische Technische Hochschule Zurich, 8092 Zurich, Switzerland

2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139

3. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139

Abstract

The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development, and are positioned to impact regenerative medicine but have yet to apply to biohybrids. Fusing microfluidics with living materials will improve tissue perfusion and maturation, and enable precise patterning of sensing, processing, and control elements. This perspective suggests future developments in advanced biohybrids.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Link

https://pnas.org/doi/pdf/10.1073/pnas.2200741119

Reference119 articles.

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4. DNA Origami Nanomachines

5. Coherent Activation of DNA Tweezers: A “SET-RESET” Logic System

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