In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction-Reference-Cited by-同舟云学术

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction

Published:2013-04-29 Issue:20 Volume:110 Page:8182-8187
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Shima F.,Yoshikawa Y.,Ye M.,Araki M.,Matsumoto S.,Liao J.,Hu L.,Sugimoto T.,Ijiri Y.,Takeda A.,Nishiyama Y.,Sato C.,Muraoka S.,Tamura A.,Osoda T.,Tsuda K.-i.,Miyakawa T.,Fukunishi H.,Shimada J.,Kumasaka T.,Yamamoto M.,Kataoka T.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference27 articles.

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2. The Guanine Nucleotide-Binding Switch in Three Dimensions

3. Addiction to Oncogenes--the Achilles Heal of Cancer

4. Essential role for oncogenic Ras in tumour maintenance

5. Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced byMycand mutantKras

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