Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference45 articles.
1. Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system;Gout;Biochem J,1992
2. Regulation of the p85/p110 phosphatidylinositol 3′-kinase: Stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit;Yu;Mol Cell Biol,1998
3. Regulation of the p85/p110α Phosphatidylinositol 3′-Kinase
4. The iSH2 domain of PI 3-kinase is a rigid tether for p110 and not a conformational switch
5. Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110 and are disrupted in oncogenic p85 mutants
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5. Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis;Nature Communications;2024-03-23
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