Kawasaki Disease and Multisystem Inflammatory Syndrome in Children

Abstract

Kawasaki disease is a vasculitis that presents with fever and affects medium-sized arteries throughout the body. Although the etiology and pathophysiology of Kawasaki disease remain unknown, the emergence of the multisystem inflammatory syndrome in children (MIS-C) in 2020 is of significant interest due to its similarity in symptoms of Kawasaki disease and its association with SARS-CoV-2. Research on the pathophysiology of MIS-C is still ongoing and is expected to contribute to the explanation of the symptoms of Kawasaki disease in the future. The diagnosis and definition, clinical features, and treatment methods of Kawasaki disease and MIS-C, which may have such an important relationship, will be summarized.